One of the very interesting things about the Soviet (and now Russian) space program is how some things seem almost eternal.
The first Sputnik launch was on an R-7 ICBM, modified for space launch. If you were to look at a picture of it, and compare it with a Soyuz launcher you saw launching last week to carry a Progress or Soyuz capsule to the ISS, it looks remarkably similar.
Sure the electronics/computers are upgraded over the years, and they added an upper stage, but what other major changes were made?
There have been many many launchers (over 1700) of the variants. But the amazing thing is how similar to the original R-7 booster they remain.
(A different and interesting (but likely unanswerable) question would be to consider the design philosophies and decisions that allowed such a long run).