Suppose large settlements are established on the moon with lots of people and industrial activity.
Based on what we know, what chemicals that are needed for human life and industry might be lacking? We know the basic breakdown of rock composition from Apollo: oxygen, silicon, iron, calcium, aluminum, magnesium are there. And we are trying to find out how much water might be at the poles in dark zones.
What about carbon and nitrogen that are needed for agriculture and plastics? What other chemicals would be needed that have not been found in exploitable concentrations?