The existing answers are correct that the same signal that ignites the SRBs also blows the nuts that hold the restraining bolts in place, so the answer is generally, no, it's not possible.
If, for some crazy reason, the nuts didn't blow, but the SRBs did ignite, things are a little different.
According to this engineer on reddit, who apparently helped design the aforementioned frangible nuts, the nuts are made of Inconel-718. Each SRB is held down by 4 of these.
According to the same engineer, the nuts and studs are actually already preloaded with about 750,000 pounds of force each. About an eighth of the (thrust - weight) of the stack would then be added to this on each post if the SRBs ignited without blowing the nuts. The aforementioned engineer performed a back-of-the-envelope calculation showing that the nuts would have a failure load around 1.65 million pounds each. Since each bolt would only have in the ballpark of 1 million pounds of force on it (including the preloaded tension,) the bolts should be able to initially hold the stack down when the SRBs light.
However, there are a couple of remaining problems.
First, the weight of the stack is rapidly decreasing due to fuel burn, meaning that the force on the bolts is rapidly increasing.
Second, and probably more importantly, the exhaust of rocket motors is really hot. While I haven't seen an exact source for the SRB exhaust specifically, NASA lists the combustion temperature of the main engines at up to 3,300 C! However, Inconel-718 will melt around 1,300 C. So, while the nuts and studs should initially hold the stack down, they'll almost certainly start heating up very quickly from the SRB exhaust and fail soon afterwards.
While I'm not sure about Inconel-718 specifically, in general, metals lose a lot of their strength well before hitting their actual melting point, so it's not likely that the bolts would be able to hold the stack down for very long. Even if they withheld all of their strength prior to melting, given the amount of energy and temperatures involved, it's quite likely that the nuts would melt well before the SRB burnout and the stack would leave the stand. No guarantees about how or in what direction it leaves the stand, but it will leave it (provided the stack doesn't disintegrate first.)
Of course, it's also entirely possible that some other failure mode will destroy the stand and/or stack before the nuts fail. The stand is designed to withstand the energy of several seconds of the SSMEs burning and a very brief encounter with the exhaust of the SRBs, but it's not designed to be able to withstand and quickly dissipate the energy of the entire 2-minute-long SRB burn.