Are there examples of Components Off The Shelf (COTS) used in the Space Transportation System?
And is NASA considering using COTS in future manned space flight systems like Orion and the SLS?
Yes, Velcro is one example. Wheat Thins are another. Did you have some specific type of component in mind?
"To keep costs down, NASA has shifted to using off-the-shelf products as much as possible. So they bought dozens of I.B.M. Thinkpad copmuters and one Epson Stylus Color 800 printer to send into space with the shuttle fleet and the new international space station."
"There are, last time I checked, about 80 laptops deployed throughout the ISS. Most of them are Lenovo T61P laptops, but there are still a few old Lenovo A31p Thinkpads floating around."
So NASA does take off-the-shelf, the first is an old quote but state they are trying to generally to save money. The second is very recent and shows they went through with it in regards to the ISS.