It goes without saying that training/conditioning one's reflexes for a situation is highly relevant to some professions. Pilots train in a computer simulator.
During the Apollo missions computers were not as ubiquitous as they now are. The CSM could be, and was checked-out in Earth orbit.
The Lunar Module (LM) however was meant for a non-Earth environment; one which could probably not be simulated - yet it would have been necessary to give the astronauts a 'feel' of the craft in reduced gravity.
The mission commander for Apollo-11 apparently did such a great job with his manual landing the shock-absorbers failed to depress. This may be merely an urban legend ... but it does draw one's attention to the question -
How did the Apollo astronauts train to land the LM in the 1/6th lunar gravity?