When the Nov 25th, 2013 SpaceX Falcon 9 v1.1 launch was scrubbed on a Monday, next launch opportunity was reported as Thursday (Thanksgiving) since the Tues/Wed days are the busiest day in the year for air travel and the FAA did not wish to restrict traffic on those days as seen here: Tweet about air space issues
So the question is, Cape Canveral/Air Force Station/Kennedy Space Center is right on the coast. Orlando is relativly far straight west of the cape. Miami and Ft. Lauderdale are both pretty far south.
It seems like rerouting around Kennedy/Cape Canveral is not that big an issue.
Unless the exclusion zone is literally monstrous? Why such a concern about the air traffic exclusion zone? How big is it really? How many flights would it affect?