The article which made me to post this question is actually about (not yet) getting to Titan, but these words provoke thought for any space exploration target, please note it's a NASA engineer telling us:
If we made a list of the thousands upon thousands of technologies that would be needed to “to achieve a manned, one-way mission to Titan”, we would find them scattered throughout the nine TRLs.
Is there actually some kind of interdisciplinary "space exploration technology database/information system" to research and analyze inter-dependencies of thousands of technologies? Obviously, they will be getting many more and also becoming even more complex. That is, "computer aided design" would involve actually a smart system telling you options and constraints pulling from existing experimental and historical data.
Who knows, maybe there is an ongoing research on something you will need a soon as it get to TRL X for your solution but just do not know it's name and can't Google it.