Gathering and delivering resources from Earth is ultimately too expensive and unsustainable for space exploration in the long term.
Emphasis has been made on extracting resources while in space, such as establishing a space elevator for launching cargo and people, a lunar or orbital production base for making products like structural elements, fuel, food, and other things you need for long term operations. Modern computers and networking technology makes it possible to do much of the work by remote control. So it's possible to have robots to work preparing for when the humans arrive, and to assist us once we get there.
Which supply chain burdens that need to be addressed in the next 30 years for more accessible private and commercial space travel?
What technologies are being developed to address these hurdles? Which have the most potential?