Thrust termination is the goal of Range Safety in the event of an errant rocket. Rendering the boosters inert is considered secondary, when possible.
The Range Safety Officers don't rely on the current positions of the vehicle to decide to terminate, but instead are looking at the IIP (Integrated Impact Point) on a map. The IIP is the point where the ...
Well, I can refer you to the Range Safety Wikipedia entry:
Two switches were used, ARM and DESTRUCT. The ARM switch shut down
propulsion for liquid propelled vehicles, and the DESTRUCT ignited the
primacord surrounding the fuel tanks. In the case of manned flight,
the vehicle would be allowed to fly to apogee before the DESTRUCT was
transmitted. This would ...