The large, low pressure engine proposed for the Sea Dragon second stage was thought to be at low risk of developing combustion instability:
The combustion chamber is of conventional design, The 30 (degree) cone half
angle and contraction area ratio of 1.8:1 allows more than enough
combustion chamber volume. The conical chamber tends to inhibit
longitudinal pressure fluctuations. The large chamber volume provides
efficient combustion and flexibility in injector design. A possible
injector configuration utilizes a shower head pattern which produces a
combustion flow field over a relatively large portion of the chamber
volume. Thus, the combustion reactions would not be as concentrated as
for other injector types, and large perturbations that trigger
combustion instability are less likely to occur. A discussion of
combustion stability is included in Appendix II-2 for a Sea Dragon
engine.
(emphasis mine)
A rigorous test campaign was proposed during which the presence or absence of instabilities would have been determined.
Unfortunately, the mentioned Appendix II-2 and its discussion of combustion stability are not included in the version of this document found on NASA NTRS or the Internet Archive.
Source: Report No. LRP 297, Volume II, page III B-8